SEGH Articles

SEGH 2014 Conference Report

08 September 2014
Northumbria University welcomed over 120 delegates from over 25 countries to SEGH 2014.

 

Northumbria University welcomed over 120 delegates from over 25 countries to SEGH2014. The meeting attracted delegates from across Europe, but also further afield from the USA, Mexico, Canada, Pakistan, Vietnam, Namibia and Nigeria, to hear the 51 papers and 40 posters presented. Human impacts on our atmosphere, lithosphere, biosphere and hydrosphere were discussed over the five days, with the linkages between human health and the environment a central focus.

In the opening session on ‘Air & Dust Pollution and Human Health’, Professor Frank Kelly (King’s College London), gave a timely and considered overview of the PM (particulate matter) burden to which populations are exposed and recent developments in evidence of how PM2.5 elicit health effects in humans. The subsequent session speakers considered how we detect, assess, model and practically tackle air pollution.

The session on ‘Environmental Iodine and the Deficiency Disorders’ generated a lively and stimulating set of papers and posters covering our current environmental knowledge and health perceptions, and highlighted ‘myths, misunderstandings and deficiencies’ along with further research needs.

As part of a special session on ‘Hydraulic fracturing (fracking) and health’ we heard a thought-provoking set of interlinked talks given by Professor Mike Stephenson (British Geological Survey), Professor Fred Worrall (Durham University), and Mr Robie Kamanyire (Public Health England). Current concerns raised in the media about the process of hydraulic fracturing were examined and discussed along with the potential public health impacts of exposures to chemical and radioactive pollutants as a result of shale gas extraction.

The central themes of risk, exposure assessment, bioavailability and bioaccessibility were explored over two days of sessions. Keynotes were given by Dr Frank Swartjes (National Institute of Public Health and the Environment (RIVM), Netherlands) and Professor Steven Sicilliano (University of Saskatchewan, Canada).  These talks, along with many of the session presenters, explored how the chemical and physical properties of soil influence the movement of pollutants from the environment into our bodies. Arsenic and Pb provided the main focus for a number of speakers, but Cd, Cu, Mg, Hg, V, along with Benzo[a]pyrene and a range of other PHEs, were also considered.   

The Conference Dinner, a Northumbrian-themed evening with local food and local music, took place in the Great Hall at Jesmond Dene House, and was attended by over 60 delegates. Photographs, taken by Ms Rosina Leonard, Geological Survey of Namibia, are available on line at Click here to view SEGH 2014

Thank you Rosina!

Finally, at the end of the week a few hardy (although they didn't realise this at the time!) delegates joined Mr Phil Hartley (Newcastle City Council) and Ms Lesley Dunlop (Northumbria University) to explore of the North-East’s industrial history and cultural heritage. However, after an amazing week of unusually good British ‘summer’ weather (yes sunshine and no rain on every day prior to the fieldtrip) our luck ran out.

Hadrian’s Wall at Cawfields. A stretch of Hadrian's Wall on a steep slope, with turrets and an impressive milecastle, probably built by the Second Legion.

 

 

 

 

But we donned hard hats, wellington boots and head torches to venture into Killhope lead mine. The mine owners hope everyone has now warmed up and dried out again! 


Killhope Lead Mine, Cowshill, Co. Durham

So just a final thank you to all who participated in SEGH 2014, and to the many new society members. Northumbria University looks forward to welcoming you to Newcastle again – but in the meantime we hope to see many of you in Bratislava in June 2015.  See www.segh.net for details.

 

 

by Jane Entwistle

(SEGH Chair 2014)

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Latest on-line papers from the SEGH journal: Environmental Geochemistry and Health

  • Genotoxic effects of PM 10 and PM 2.5 bound metals: metal bioaccessibility, free radical generation, and role of iron 2018-10-09

    Abstract

    The present study was undertaken to examine the possible genotoxicity of ambient particulate matter (PM10 and PM2.5) in Pune city. In both size fractions of PM, Fe was found to be the dominant metal by concentration, contributing 22% and 30% to the total mass of metals in PM10 and PM2.5, respectively. The speciation of soluble Fe in PM10 and PM2.5 was investigated. The average fraction of Fe3+ and Fe2+ concentrations in PM2.5 was 80.6% and 19.3%, respectively, while in PM2.5 this fraction was 71.1% and 29.9%, respectively. The dominance of Fe(III) state in both PM fractions facilitates the generation of hydroxyl radicals (·OH), which can damage deoxyribose nucleic acid (DNA), as was evident from the gel electrophoresis study. The DNA damage by ·OH was supported through the in silico density functional theory (DFT) method. DFT results showed that C8 site of guanine (G)/adenine (A) and C6 site of thymine (T)/cytosine (C) would be energetically more favorable for the attack of hydroxyl radicals, when compared with the C4 and C5 sites. The non-standard Watson–Crick base pairing models of oxidative products of G, A, T and C yield lower-energy conformations than canonical dA:dT and dG:dC base pairing. This study may pave the way to understand the structural consequences of base-mediated oxidative lesions in DNA and its role in human diseases.

  • A systematic review on global pollution status of particulate matter-associated potential toxic elements and health perspectives in urban environment 2018-10-08

    Abstract

    Airborne particulate matter (PM) that is a heterogeneous mixture of particles with a variety of chemical components and physical features acts as a potential risk to human health. The ability to pose health risk depends upon the size, concentration and chemical composition of the suspended particles. Potential toxic elements (PTEs) associated with PM have multiple sources of origin, and each source has the ability to generate multiple particulate PTEs. In urban areas, automobile, industrial emissions, construction and demolition activities are the major anthropogenic sources of pollution. Fine particles associated with PTEs have the ability to penetrate deep into respiratory system resulting in an increasing range of adverse health effects, at ever-lower concentrations. In-depth investigation of PTEs content and mode of occurrence in PM is important from both environmental and pathological point of view. Considering this air pollution risk, several studies had addressed the issues related to these pollutants in road and street dust, indicating high pollution level than the air quality guidelines. Observed from the literature, particulate PTEs pollution can lead to respiratory symptoms, cardiovascular problems, lungs cancer, reduced lungs function, asthma and severe case mortality. Due to the important role of PM and associated PTEs, detailed knowledge of their impacts on human health is of key importance.

  • Interactions between polycyclic aromatic hydrocarbons and epoxide hydrolase 1 play roles in asthma 2018-10-06

    Abstract

    Asthma, as one of the most common chronic diseases in children and adults, is a consequence of complex gene–environment interactions. Polycyclic aromatic hydrocarbons (PAHs), as a group of widespread environmental organic pollutants, are involved in the development, triggering and pathologic changes of asthma. Various previous studies reported the critical roles of PAHs in immune changes, oxidative stress and environment–gene interactions of asthma. EPHX1 (the gene of epoxide hydrolase 1, an enzyme mediating human PAH metabolism) had a possible association with asthma by influencing PAH metabolism. This review summarized that (1) the roles of PAHs in asthma—work as risk factors; (2) the possible mechanisms involved in PAH-related asthma—through immunologic and oxidative stress changes; (3) the interactions between PAHs and EPHX1 involved in asthma—enzymatic activity of epoxide hydrolase 1, which affected by EPHX1 genotypes/SNPs/diplotypes, could influence human PAH metabolism and people’s vulnerability to PAH exposure. This review provided a better understanding of the above interactions and underlying mechanisms for asthma which help to raise public’s concern on PAH control and develop strategies for individual asthma primary prevention.